Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.2
USERS' SCORE
Good
Based on 11 Reviews
8.1
Supplement Facts
Serving Size: 3 Capsules
Serving Per Container:  30
Amount Per Serving
%DV
Magnesium (from 2,000 mg Magnesium L-Threonate)
144 mg
34%

Top Medical Research Studies

7
Magnesium reduces brain injury markers
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.

The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Read More
9.5
Magnesium's role in brain tumor treatment
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.

Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
Read More
8
Magnesium nanoparticles reduce neuroblastoma growth
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.

When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
Read More

Most Useful Reviews

9
Enhanced memory reported
69 people found this helpful
This is the best form of magnesium for brain and nervous system health, unlike other forms that can be laxative. I have been taking this form almost continuously for two years, leading to noticeable improvements in my memory and attention. I wholeheartedly recommend it; it also alleviates leg cramps and restless legs syndrome.
Read More
8
Nervous system support
34 people found this helpful
Magnesium threonate supports the central nervous system, chosen based on specific needs (e.g., relaxation, muscle support). Due to its cost, it should be used judiciously. I take it regularly due to my hearing loss, and I have noticed significant improvements in my symptoms! It certainly makes a difference!
Read More
9
Excellent for anxiety
8 people found this helpful
Excellent magnesium threonate; it operates gently due to its dosage. I've tried various brands, and this one worked for me without the heavy feeling I experienced before. Magnesium threonate is unique as it penetrates the blood-brain barrier, improving cognitive functions and providing quick relief during anxiety. I use it for post-trauma recovery and find it invaluable, though it's pricier than other forms. It can be combined with malate and bisglycinate as needed. I fully endorse this threonate!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.2
  • All Researches
9.5
Magnesium's role in brain tumor treatment
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.

Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
Read More
8
Magnesium nanoparticles reduce neuroblastoma growth
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.

When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
Read More
7
Magnesium reduces brain injury markers
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.

The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Enhanced memory reported
69 people found this helpful
This is the best form of magnesium for brain and nervous system health, unlike other forms that can be laxative. I have been taking this form almost continuously for two years, leading to noticeable improvements in my memory and attention. I wholeheartedly recommend it; it also alleviates leg cramps and restless legs syndrome.
Read More
8
Nervous system support
34 people found this helpful
Magnesium threonate supports the central nervous system, chosen based on specific needs (e.g., relaxation, muscle support). Due to its cost, it should be used judiciously. I take it regularly due to my hearing loss, and I have noticed significant improvements in my symptoms! It certainly makes a difference!
Read More
9
Excellent for anxiety
8 people found this helpful
Excellent magnesium threonate; it operates gently due to its dosage. I've tried various brands, and this one worked for me without the heavy feeling I experienced before. Magnesium threonate is unique as it penetrates the blood-brain barrier, improving cognitive functions and providing quick relief during anxiety. I use it for post-trauma recovery and find it invaluable, though it's pricier than other forms. It can be combined with malate and bisglycinate as needed. I fully endorse this threonate!
Read More
7.5
Surprisingly effective
8 people found this helpful
I was surprised! I took one capsule in the morning during a sleep-deprived state, and unexpectedly, my brain felt clear and alert. I almost forgot I had taken Magtein, but the effect was undeniable. I recommend it for individuals who struggle with clarity or forgetfulness due to daily cognitive fatigue!
Read More
7.5
Improved cognitive function
212 people found this helpful
Excellent thing! The brain works better; even my dreams resemble a Hollywood film with captivating plots and vivid imagery! We began taking it as a family, including my children aged 6 (2 capsules daily) and 4 (1 capsule daily). As a result, my children have become calmer and no longer resist reading their primer and doing other homework from speech therapy. It's as if their brains have adjusted and now function primarily in a cognitive manner. However, I'm uncertain what will happen if I stop giving it to them. Nine capsules a day for a family is quite expensive. Please follow your doctor's advice.
Read More

Frequently Asked Questions

7.5
Benefits for sleep
113 people found this helpful
Magnesium threonate has a remarkable effect on the brain; it's prescribed for nervous system issues. Many experience deeper, more efficient sleep, and muscle tics often diminish. The benefits can usually be felt within a week or two. I highly recommend trying it!
9
Enhanced memory reported
69 people found this helpful
This is the best form of magnesium for brain and nervous system health, unlike other forms that can be laxative. I have been taking this form almost continuously for two years, leading to noticeable improvements in my memory and attention. I wholeheartedly recommend it; it also alleviates leg cramps and restless legs syndrome.
7.5
Supports brain health
17 people found this helpful
The best type of magnesium for brain and neurological issues! If you experience anxiety or sleep trouble, I highly advise trying Magtein for several weeks. Magnesium is inherently calming, and when combined with L-threonate, it reaches the brain effectively. After struggling with sleep and muscle twitches, I found Magtein to be beneficial. The dosage is reasonable, allowing you to take what works for you. I recommend it!
4
Direct brain effect
5 people found this helpful
I tried this magnesium as it reaches the brain directly but found it less effective than others. The effectiveness varies person to person.
8
Nervous system support
34 people found this helpful
Magnesium threonate supports the central nervous system, chosen based on specific needs (e.g., relaxation, muscle support). Due to its cost, it should be used judiciously. I take it regularly due to my hearing loss, and I have noticed significant improvements in my symptoms! It certainly makes a difference!
7.5
Improved cognitive function
212 people found this helpful
Excellent thing! The brain works better; even my dreams resemble a Hollywood film with captivating plots and vivid imagery! We began taking it as a family, including my children aged 6 (2 capsules daily) and 4 (1 capsule daily). As a result, my children have become calmer and no longer resist reading their primer and doing other homework from speech therapy. It's as if their brains have adjusted and now function primarily in a cognitive manner. However, I'm uncertain what will happen if I stop giving it to them. Nine capsules a day for a family is quite expensive. Please follow your doctor's advice.
9
Excellent for anxiety
8 people found this helpful
Excellent magnesium threonate; it operates gently due to its dosage. I've tried various brands, and this one worked for me without the heavy feeling I experienced before. Magnesium threonate is unique as it penetrates the blood-brain barrier, improving cognitive functions and providing quick relief during anxiety. I use it for post-trauma recovery and find it invaluable, though it's pricier than other forms. It can be combined with malate and bisglycinate as needed. I fully endorse this threonate!
7.5
Surprisingly effective
8 people found this helpful
I was surprised! I took one capsule in the morning during a sleep-deprived state, and unexpectedly, my brain felt clear and alert. I almost forgot I had taken Magtein, but the effect was undeniable. I recommend it for individuals who struggle with clarity or forgetfulness due to daily cognitive fatigue!
9
Cognitive function support
34 people found this helpful
Excellent! This particular form of magnesium can pass through the blood-brain barrier. Studies indicate that magnesium L-threonate positively impacts cognitive abilities, particularly memory and sleep quality. Although its magnesium content is only about 3%, threonate has high bioavailability, making it a preferable option for enhancing cognitive functions. It should be taken on an empty stomach for optimal absorption.
7
Magnesium reduces brain injury markers
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.

The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
9.5
Magnesium's role in brain tumor treatment
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.

Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
8
Magnesium nanoparticles reduce neuroblastoma growth
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.

When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.

References

  1. Nalci OB, Nadaroglu H, Genc S, Hacimuftuoglu A, Alayli A. The effects of MgS nanoparticles-Cisplatin-bio-conjugate on SH-SY5Y neuroblastoma cell line. Mol Biol Rep. 2020;47:9715. 10.1007/s11033-020-05987-2
  2. Zappia F, Verzicco I, Simoni R, Ferrari M, Coghi P, et al. Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment. Acta Biomed. 2020;91:365. 10.23750/abm.v91i2.8685
  3. Mirrahimi B, Mortazavi A, Nouri M, Ketabchi E, Amirjamshidi A, et al. Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial. Acta Neurochir (Wien). 2015;157:985. 10.1007/s00701-015-2376-x
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