Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Read More
9.5
Magnesium's role in brain tumor treatment
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.
When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
Read More
Most Useful Reviews
9
Enhanced memory reported
69 people found this helpful
This is the best form of magnesium for brain and nervous system health, unlike other forms that can be laxative. I have been taking this form almost continuously for two years, leading to noticeable improvements in my memory and attention. I wholeheartedly recommend it; it also alleviates leg cramps and restless legs syndrome.
Read More
8
Nervous system support
34 people found this helpful
Magnesium threonate supports the central nervous system, chosen based on specific needs (e.g., relaxation, muscle support). Due to its cost, it should be used judiciously. I take it regularly due to my hearing loss, and I have noticed significant improvements in my symptoms! It certainly makes a difference!
Read More
9
Excellent for anxiety
8 people found this helpful
Excellent magnesium threonate; it operates gently due to its dosage. I've tried various brands, and this one worked for me without the heavy feeling I experienced before. Magnesium threonate is unique as it penetrates the blood-brain barrier, improving cognitive functions and providing quick relief during anxiety. I use it for post-trauma recovery and find it invaluable, though it's pricier than other forms. It can be combined with malate and bisglycinate as needed. I fully endorse this threonate!
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.
When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
Read More
7
Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.1
All Reviews
Positive Reviews
Negative Reviews
9
Enhanced memory reported
69 people found this helpful
This is the best form of magnesium for brain and nervous system health, unlike other forms that can be laxative. I have been taking this form almost continuously for two years, leading to noticeable improvements in my memory and attention. I wholeheartedly recommend it; it also alleviates leg cramps and restless legs syndrome.
Read More
8
Nervous system support
34 people found this helpful
Magnesium threonate supports the central nervous system, chosen based on specific needs (e.g., relaxation, muscle support). Due to its cost, it should be used judiciously. I take it regularly due to my hearing loss, and I have noticed significant improvements in my symptoms! It certainly makes a difference!
Read More
9
Excellent for anxiety
8 people found this helpful
Excellent magnesium threonate; it operates gently due to its dosage. I've tried various brands, and this one worked for me without the heavy feeling I experienced before. Magnesium threonate is unique as it penetrates the blood-brain barrier, improving cognitive functions and providing quick relief during anxiety. I use it for post-trauma recovery and find it invaluable, though it's pricier than other forms. It can be combined with malate and bisglycinate as needed. I fully endorse this threonate!
Read More
7.5
Surprisingly effective
8 people found this helpful
I was surprised! I took one capsule in the morning during a sleep-deprived state, and unexpectedly, my brain felt clear and alert. I almost forgot I had taken Magtein, but the effect was undeniable. I recommend it for individuals who struggle with clarity or forgetfulness due to daily cognitive fatigue!
Read More
7.5
Improved cognitive function
212 people found this helpful
Excellent thing! The brain works better; even my dreams resemble a Hollywood film with captivating plots and vivid imagery! We began taking it as a family, including my children aged 6 (2 capsules daily) and 4 (1 capsule daily). As a result, my children have become calmer and no longer resist reading their primer and doing other homework from speech therapy. It's as if their brains have adjusted and now function primarily in a cognitive manner. However, I'm uncertain what will happen if I stop giving it to them. Nine capsules a day for a family is quite expensive. Please follow your doctor's advice.
A brain tumor is an abnormal growth of cells in the brain or central spinal canal. These tumors can be classified as either benign (non-cancerous) or malignant (cancerous), and they can originate from the brain tissue itself (primary brain tumors) or spread to the brain from other parts of the body (secondary or metastatic brain tumors). Symptoms may vary widely depending on the tumor's location, size, and type, but common indicators include headaches, seizures, cognitive or behavioral changes, and motor skill deficiencies. Diagnosing a brain tumor typically involves imaging tests such as MRI or CT scans, followed by a biopsy to determine the type of tumor.
Treatment for brain tumors depends on several factors, including the tumor type, size, and location, as well as the patient's overall health. Common treatment options include surgery to remove the tumor, radiation therapy, and chemotherapy. While advancements in medical technology have improved treatment outcomes significantly—enabling more precise targeting of tumors and minimizing damage to surrounding healthy brain tissue—challenges still exist. It's crucial for patients to discuss all available options with their healthcare providers to determine the best course of action tailored to their specific situation.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Based on user reviews, many individuals report noticing benefits from magnesium threonate within a week or two of consistent use Read Review. Users have experienced improvements in memory, cognitive clarity, and overall brain function, with some noting significant changes in their daily cognitive abilities after taking the supplement regularly Read Review. Additionally, several reviews mention that results can be felt relatively quickly, especially for issues related to anxiety and sleep disturbances Read Review.
However, it's essential to consider that individual responses to the supplement can vary greatly. Some users found that the effectiveness of magnesium threonate was less pronounced compared to other supplements Read Review. This variability highlights the importance of giving the supplement a fair trial while also consulting with a healthcare provider for personalized advice regarding usage and expectations.
The role of magnesium in brain tumor treatment is supported by several studies, although the evidence is still unfolding. One research investigated the effects of magnesium sulfate (MgSO4) in patients undergoing surgery for brain tumors and found that it helped reduce certain protein levels associated with brain injury post-surgery. While this suggests some benefits of magnesium, the overall functional outcomes for patients did not show significant improvement, indicating that while magnesium may play a supportive role, it is not a standalone treatment for brain tumors [3].
Another study highlighted the importance of magnesium in the context of treatment-related neurological issues, showing a case where intravenous magnesium supplementation led to a rapid improvement in a patient with breast cancer suffering from low magnesium levels after chemotherapy. This points to the potential role of magnesium in managing treatment side effects that can exacerbate neurological symptoms in brain tumor patients [2]. Additionally, while magnesium sulfide nanoparticles demonstrated promising effects in reducing cancer cell viability in neuroblastoma cells, translating these findings specifically to broader brain tumor contexts requires further investigation [1]. Overall, while there is some supportive data regarding magnesium's role in brain tumor care, more research is needed to establish its efficacy as a treatment aid.
Users have reported a variety of improvements in symptoms after taking magnesium threonate, particularly regarding cognitive function and relaxation. For instance, one user noted significant enhancements in memory and attention after two years of regular use, also highlighting the relief of leg cramps and restless legs syndrome Read Review. Another review emphasized the supplement's positive impact on symptoms related to hearing loss, noting meaningful improvements Read Review. Additionally, users have experienced clearer thinking and improved dream vividness, suggesting that it may also influence the quality of sleep Read Review.
Moreover, several individuals mentioned a reduction in anxiety and better overall brain function, which they attributed to magnesium threonate's unique ability to penetrate the blood-brain barrier Read Review. While many reported quick benefits, especially for cognitive fatigue Read Review and deeper sleep Read Review; it's important to remember that individual experiences can vary, with some finding it less effective than other magnesium forms Read Review.
Users report that combining magnesium threonate with other magnesium forms such as malate and bisglycinate can be beneficial, as these combinations might enhance various effects based on individual needs. One review highlights that magnesium threonate's ability to penetrate the blood-brain barrier makes it particularly effective for cognitive functions and anxiety relief, suggesting that users often find it complements other supplements well for comprehensive brain health management Read Review.
However, individual responses to magnesium threonate vary significantly. While some find it to be a superior option, others reported feeling less efficacy compared to other magnesium types, emphasizing the importance of finding the right combination that works best for them. Users are encouraged to consult healthcare professionals to tailor supplement regimens that suit their specific health circumstances and supplement goals Read Review.
Users report that magnesium threonate, specifically, is highly regarded for its effectiveness in treating brain-related issues. Many users recommend this form for its ability to penetrate the blood-brain barrier, thus enhancing cognitive function and providing relief from symptoms related to anxiety and sleep disturbances. For example, one user noted significant improvements in memory and attention after taking magnesium threonate consistently for two years Read Review. Another shared their experience of feeling clearer and more alert after just one capsule, indicating its potency even at low doses Read Review.
In terms of dosage, there seems to be no one-size-fits-all answer. Users have reported varied dosages depending on individual needs, such as children taking 1-2 capsules per day Read Review. However, it is emphasized that the magnesium content itself is lower than other forms at around 3%, but its bioavailability makes it a preferable option for enhancing cognitive function Read Review. Overall, while the recommended doses vary, users suggest starting low and adjusting based on personal response, and consulting with a healthcare professional is advisable.
7.5
Benefits for sleep
113 people found this helpful
Magnesium threonate has a remarkable effect on the brain; it's prescribed for nervous system issues. Many experience deeper, more efficient sleep, and muscle tics often diminish. The benefits can usually be felt within a week or two. I highly recommend trying it!
9
Enhanced memory reported
69 people found this helpful
This is the best form of magnesium for brain and nervous system health, unlike other forms that can be laxative. I have been taking this form almost continuously for two years, leading to noticeable improvements in my memory and attention. I wholeheartedly recommend it; it also alleviates leg cramps and restless legs syndrome.
7.5
Supports brain health
17 people found this helpful
The best type of magnesium for brain and neurological issues! If you experience anxiety or sleep trouble, I highly advise trying Magtein for several weeks. Magnesium is inherently calming, and when combined with L-threonate, it reaches the brain effectively. After struggling with sleep and muscle twitches, I found Magtein to be beneficial. The dosage is reasonable, allowing you to take what works for you. I recommend it!
4
Direct brain effect
5 people found this helpful
I tried this magnesium as it reaches the brain directly but found it less effective than others. The effectiveness varies person to person.
8
Nervous system support
34 people found this helpful
Magnesium threonate supports the central nervous system, chosen based on specific needs (e.g., relaxation, muscle support). Due to its cost, it should be used judiciously. I take it regularly due to my hearing loss, and I have noticed significant improvements in my symptoms! It certainly makes a difference!
7.5
Improved cognitive function
212 people found this helpful
Excellent thing! The brain works better; even my dreams resemble a Hollywood film with captivating plots and vivid imagery! We began taking it as a family, including my children aged 6 (2 capsules daily) and 4 (1 capsule daily). As a result, my children have become calmer and no longer resist reading their primer and doing other homework from speech therapy. It's as if their brains have adjusted and now function primarily in a cognitive manner. However, I'm uncertain what will happen if I stop giving it to them. Nine capsules a day for a family is quite expensive. Please follow your doctor's advice.
9
Excellent for anxiety
8 people found this helpful
Excellent magnesium threonate; it operates gently due to its dosage. I've tried various brands, and this one worked for me without the heavy feeling I experienced before. Magnesium threonate is unique as it penetrates the blood-brain barrier, improving cognitive functions and providing quick relief during anxiety. I use it for post-trauma recovery and find it invaluable, though it's pricier than other forms. It can be combined with malate and bisglycinate as needed. I fully endorse this threonate!
7.5
Surprisingly effective
8 people found this helpful
I was surprised! I took one capsule in the morning during a sleep-deprived state, and unexpectedly, my brain felt clear and alert. I almost forgot I had taken Magtein, but the effect was undeniable. I recommend it for individuals who struggle with clarity or forgetfulness due to daily cognitive fatigue!
9
Cognitive function support
34 people found this helpful
Excellent! This particular form of magnesium can pass through the blood-brain barrier. Studies indicate that magnesium L-threonate positively impacts cognitive abilities, particularly memory and sleep quality. Although its magnesium content is only about 3%, threonate has high bioavailability, making it a preferable option for enhancing cognitive functions. It should be taken on an empty stomach for optimal absorption.
7
Magnesium reduces brain injury markers
Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial.
We examined how intravenous magnesium sulfate (MgSO4) affects patients undergoing surgery for brain tumors. Sixty patients were divided into two groups: one received magnesium treatment, while the other received a placebo.
The results showed that magnesium lowered significant protein levels linked to brain injury after surgery. However, it didn’t substantially change the overall functional outcomes for the patients. While MgSO4 appears safe and beneficial in reducing specific markers, more research is necessary to fully grasp magnesium's role in brain injury recovery.
9.5
Magnesium's role in brain tumor treatment
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment.
We explored the relationship between low magnesium levels and the development of posterior reversible encephalopathy syndrome (PRES) in a patient with advanced breast cancer. After treatment with diuretics and chemotherapy, this patient experienced serious neurological symptoms alongside low magnesium levels.
Following intravenous magnesium supplementation, the patient showed remarkable improvement within 18 hours. This suggests that low magnesium, potentially linked to her treatment regimens, might have played a role in her condition. Thus, monitoring magnesium levels could be crucial in cancer care.
We explored how magnesium sulfide nanoparticles (MgS NPs) affect the SH-SY5Y neuroblastoma cell line, which is a significant challenge in treating brain cancer. Using a green synthesis method, we created MgS NPs and tested their effects in cultured cells.
When applied at various doses, we observed that 75 µg/mL MgS NPs reduced cancer cell viability by nearly half. The treatment also increased oxidant levels in the cells, aligning with our findings from cytotoxicity tests. Overall, it appears that MgS NPs effectively hinder the growth of neuroblastoma cells.
References
Nalci OB, Nadaroglu H, Genc S, Hacimuftuoglu A, Alayli A. The effects of MgS nanoparticles-Cisplatin-bio-conjugate on SH-SY5Y neuroblastoma cell line. Mol Biol Rep. 2020;47:9715. 10.1007/s11033-020-05987-2
Zappia F, Verzicco I, Simoni R, Ferrari M, Coghi P, et al. Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment. Acta Biomed. 2020;91:365. 10.23750/abm.v91i2.8685
Mirrahimi B, Mortazavi A, Nouri M, Ketabchi E, Amirjamshidi A, et al. Effect of magnesium on functional outcome and paraclinical parameters of patients undergoing supratentorial craniotomy for brain tumors: a randomized controlled trial. Acta Neurochir (Wien). 2015;157:985. 10.1007/s00701-015-2376-x